Acute phase protein concentrations in serum and milk from healthy cows, cows with clinical mastitis and cows with extramammary inflammatory conditions.
نویسندگان
چکیده
The concentrations of the two acute phase proteins, serum amyloid A and haptoglobin, in serum and milk were compared in 10 cows with clinical mastitis, 11 cows with extramammary inflammatory conditions and 10 clinically healthy control cows. The concentrations of both acute phase proteins were higher in the serum and milk of the cows with mastitis than in the cows in the other two groups. Four of the cows with extramammary inflammatory conditions had serum amyloid A concentrations in serum above 100 microg/ml, but negligible concentrations in milk, indicating that a pathogen must be present in the mammary gland for serum amyloid A to accumulate in milk. The acute phase protein concentrations in milk increased significantly with increasing somatic cell count, suggesting that they may be indicators of the severity of an infection.
منابع مشابه
A comparison of milk protein status of healthy and mastitic cows under denaturing conditions
Mastitis is one of the most important diseases of dairy cattle in the world. The identification and characterization of the constituent proteins in milk can be useful for studying the biochemistry and pathogenesis of mastitis. In this study, the electrophoretic patterns of milk from 10 healthy and 30 mastitic cows were studied. All of the latter milk samples were California Mastitis Test (CMT) ...
متن کاملEvaluation of serum and milk amyloid A in some inflammatory diseases of cattle
This study was designed to evaluate serum and milk amyloid A (SAA) as an inflammatory indicator in inflammatory diseases. Twenty clinically healthy cows and 100 cows with various inflammatory diseases were selected for this study. Blood samples were collected from the coccygeal vein of both healthy and diseased groups. Milk samples were taken from four quarters of both groups. Milk samples of f...
متن کاملDetermination of milk and blood concentrations of lipopolysaccharide-binding protein in cows with naturally acquired subclinical and clinical mastitis.
Blood and milk concentrations of the acute phase protein lipopolysaccharide-binding protein (LBP) were evaluated in cows with naturally occurring mastitis. Blood and milk samples were collected from 101 clinically healthy dairy cows and 17 dairy cows diagnosed with clinical mastitis, and the LBP concentrations of the samples were measured by an ELISA. Concentrations of LBP were greater in the b...
متن کاملChanges of acute-phase proteins during different phases of the estrous cycle in Ovsynch-synchronized Holstein cows
Background: Acute-phase proteins (APPs) may be increased due to different stresses during estrus phase in farm animals. Aims: Determining changes of APPs at different phases of non-synchronized estrous cycle group (NSEG), and Ovsynch-synchronized estrous cycle group (SEG) in Holstein cows. Methods: Twelve non-pregnant clinically and paraclinicaly healthy Holstein cows with a body condition scor...
متن کاملTransgenic cows that produce recombinant human lactoferrin in milk are not protected from experimental Escherichia coli intramammary infection.
This is the first study describing an experimental mastitis model using transgenic cows expressing recombinant human lactoferrin (rhLf) in their milk. The aim of the study was to investigate the concentrations in milk and protective effects of bovine and recombinant human lactoferrin in experimental Escherichia coli mastitis. Experimental intramammary infection was induced in one udder quarter ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Veterinary record
دوره 154 12 شماره
صفحات -
تاریخ انتشار 2004